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NBME 19 Answers

nbme19/Block 1/Question#1 (reveal difficulty score)
53 yo woman w/GERD. Diet change, stress ...
Omeprazole πŸ” / πŸ“Ί / 🌳
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 +27 
submitted by βˆ—monoloco(150),
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I aevh gdrrdaee etsripuc as teh bbngiur fo -.neoooebnb-n My tdsyu rnatrep nda I tnkih shit is a luyper ilinodniafte iosqnet.u ,Yes upercsti coldu aslo eb dapprte ari. xoCen,tt I ssgu.e


 +18 
submitted by βˆ—ajguard26(51),
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So utahhglo ptMlrsiooos EDSO iaecnesr smucu pouictrdno dna si grt-ptatvieesroco n(da in FA oesd staet ttah ti eersscdae ciad dp)rcouiot,n yetebrh endsgiraec pytsmoms nad ginida in heg,alin oomelaepzr is hte rm"eo rroc"cte coihe.c shiT si sbueeac erepomazol si a mpnotr-uopp iiorb,ihnt cihhw iwll atc tlicedyr on eht torpno pmups fo hte hcamsot nda sedeacer eht fnfegdnio negat orme ahnt het mipoostlrso ilw.l eoerf,hTre it si eht sitrf inle dugr rfo RGDE.

an_improved_me  These questions can be so frustrating... I mean most people know PPIs are your go to when considering GERD / peptic ulcer disease... but when you speicfically add "both relieving Sx ... promoting healing", why even add a drug that specifically and directly does both... I mean PPIs promote healing, but so indirectly. This hurts my heart +3  
chaosawaits  Seriously, FA2019, p393 specifically states misoprostol "increases production and secretion of gastric mucous barrier and decreases acid production" What does it say for omeprazole, you might ask? "Irreversibly inhibits H+/K+ ATPase in stomach parietal cells" and that's it. +  



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