Kid had a viral URI then took aspirn -> Reye syndrome, a hepatic encephalopathy. There is increased ammonia production because of the liver damage, leading to hyperammonemia. This gets to the brain, is ocnverted to glutamine (an osmolyte). This causes the brain swelling.
It's not E) viral encephalitis because it implies the virus is directly causing the encephalitis. Instead, the viral infection -> aspirin -> liver damage -> ammonia -> crosses BBB -> converted to glutamine -> draws in water -> cerebral edema
Immunohistochemical labeling uses antibodies as markers for what they want to find. In this case, we're suspecting gastrin given the symptoms
Note: You should revise the function, stimulation, and site of release for each of the hormones mentioned as well
REFERENCE: Zollinger-Ellison Syndrome
This is metastatic renal cell carcinoma (FA2020 p605) for the following reasons:
I cell disease —inherited lysosomal storage disorder (autosomal recessive); defect in N-acetylglucosaminyl-1-phosphotransferase --> failure of the Golgi to phosphorylate mannose residues (decrease mannose-6-phosphate) on glycoproteins --> proteins are secreted extracellularly rather than delivered to lysosomes