Kdi adh a lirva UIR nhte ootk npasri ;-gt& yeRe noredmsy, a thiepca pleyhhtancpeao. eTerh si aseneicrd aomanmi otidcrnuop uabesce of eht eirlv ,maedag ndgelai ot mnmampoyare.hie iTsh egts ot eht rinab, is octedvenr to eagmniult an( tolm.yoes) Thsi sscaeu teh nraib insgllew.

Ist' tno E) rvila sehalintcpie escbaue ti mielpsi eth iursv is credylit gusiacn the neheiapti.lsc ,e stadIn het irlva cftenioin -> nriiaps t;-&g rilve mdgaae g-&t; ommanai ;gt-& ssseorc BBB &;-gt drcveonet to auetngiml ;&t-g awdrs in teraw t&-g; rrcabele meade

gcsn:0seamluhpeop1al/hi71ea/att-h8hpsotim/t.nyslp0eeb.t0tctltct/daorepn/ies

• uBgnirn Aiomdanbl iaPn sruho rtefa atinge = cisrGta rclue
• kBacl oslsto ofr 2 ydas = ???
• ytcfearoRr to OCT caAdtnis dan H2 lkrBceso
• tngwSiea and Lwo PB
• eicactnrPa sMas = somt lekliy SATIOMARNG

oaIomccehilmnmutshi blgleain uses iantesdibo as erkasrm ofr hatw yhte natw to fdni. nI htis ec,as r'ewe tgipncuses grstina gievn the msmyospt

e:toN Yuo dulsoh seriev het uf,toninc utlmoisa,tin and iets of aeelsre ofr ecah of hte oehnosmr metdnineo sa ewll

EENEEC:RF Roeg-nZlrlosiEnlli Syoenmdr

hTis is ctemsattai rlnae llec camrniaoc F2020(A 05p6) rfo het gfoiwlonl esosa:rn

• alhycPioeymt - hits si the irapyrm u,lec sa ti si aesdaotcsi wthi ecoiptc OPE (yoeton)rrphiti nsetcioer in ocaealitsnappr serdsnoym 0(0A22F 2,82p) hicwh cna eb aduces by heomy,ootpmccrhoa arlne lelc rnacaom,ic aolpeuctlrelh ca,rcaiomn maabilahstomgeon adn ioelmomay. fO hseet, oynl lriev dna yenidk oudlw be a ieccho evgin nda houlaacltrplee coracanmi is ecicortnr cebseau eh did ton vaeh yna ataicsdsoe ngfiind of juindae,c pageamly,ohet tsceis,a or rnoxaiea 00AF(22 3p).29 Pusl, het erliv odse not oncmlmyo stmatiseaze to barin esehraw nieydk does 00AF2(2 )p232
• alyercmpaiecH - htis is lkelyi inatviecid fo TrHPP ecios,nter nda enral lecl aiccomnra si eno fo teh nescrac ttah acn od hist. eorwHe,v isth si yiaflr fcinsoicnpe sa terhe rea amyn ecrcsna htat anc eteecsr H.rPPT
• umHaaitaer - gestvegusi of ky/airriydnenu ctatr nlioevvmnte
• ivetNgea rof rncnacoroiymbeci iennagt - hist is a ipncoicsefn remark anylmi rfo nloco dna nacarpitec ncecras 0(220AF p622)

I llce deiessa iedihne—tr sylmaools roagset rsdrdeoi saaotolum( s)ees;recvi dtfcee ni aap1p-lcugtnmseoahhycoyo-e-Nlnrsifrasltse ;g&t-- luirafe of the iGolg ot aypreltshhpoo oanmens ureiseds ee(sarcde ne6-maepto)hspasno-h on iltscynproego g-&t-; e ntspori are rseteedc elaxalullyetcrr ehartr nhat derldeiev ot osmlessyo

I ithnk sith si ynSdgorltieso roestlarsic amr(hw)roetd is a owumdnror eswoh raaevl vlei ni lsoi and how anc ucase unamployr .daeeiss tI has the ytliiba ot eptnreaet kisn frmo teh islo but acn lsao be aeitnbdo by ggnsnieit ecefs ncmtnstaoaie osli 0F0A2(2 9)p1 5/wwisfhc/l:vshewttcrsq_oo/p/lsd.ts.gn.pntmaaorgtoe/sdyin/aifeg

ostM eltitnsina uormsonwdr are ef-oaacrll tureo tecexp yieotndsrsogl wichh nac lsoa retnaepte ,sikn owkomorh rtoc(ean rmaic)esaun icwhh lnyo peeartestn s,ikn dna ceralilihtn iwhch anc come fmro dnkudeoecro setam cia(lsleyep rop)k btu hoswe ompssmyt do otn hcamt atth of the p.ietant illnaicrheT ealvra rnete the lbdoo temsar adn ecfitn mcselu adn acn asol ceasu hioirnsitsc with e,fver ue,snaa vmiogi,tn rtroeblpaii e,maed and myalagi.

CTAEU claoohl hinsibit CPY → raneIescd lbtyabiolvaiiai of omeoetiachnnp

OCIRCNH olchlao diusnce YPC → oitundIcn fo eymtchrcoo P405 mnyesze thta tetviaca aeephimncatno to a hxiopetctao aioebttlem

I tgo sthi wrong cuebeas I dsseuam iorchnc haolloc enmat eyars adn .saeyr I gessu a dneekew illw ucsf?ife

Hsetl,noy cukf htis rpbom.el

nNcai(i Vti 3B)
- htibnsii islpslioy ( omnehor ivteinsse pliesa ) dna ehtpaci LDLV tnssihsey ecs/eiortn .

eiSd etsefcf :Fiaal c lnhgufsi , yaoscednr to atrpgnnaoldsi aesleer . ePr teatr thwi DSSNIA
- sAol cauess ;rlaigHpyyemec nda eiyraimcruHpe , sa cshu aivdo in Gytou psteiatn nda ieiDctabs

In yrkoset,aue het 5' hnneegaoutsymil mG)7( pac si ttoinpmra ni teh notiitiain of ontstranial sbuceae cyoaritkeu ioititnnia sfarotc seF)(I efitidny het apc and leph esmlbaes the erbismoo ta htta teis 0FA02(2 4p.)5

heT ebaecsn of a 5' 7mG cap ouwdl stuh rruqeie a fitrdfeen qeseuenc to lalwo ananltstiro atiiiiotnn nda olibmsaor etrny (i.e. na ternnila ambloiros yntre ).stei

Teh 5' and '3 teulsadnrtan riensog aer reom irnotmpta in trligoaenu fo onsntiatalr adn iiornetamnt fo lasrttn,iano ,eliyrpstcvee adn ihrte scneeba ludow not adi nnsilottara of teh rvial .NmRA Teh '3 poAl-y lati si ratomnpit rof toonieprtc fo akcyoieutr RNAm rofm gnrdteiaaod dan gndiai in rtnoieapoxt omrf eth secl;unu sti cnsebea wldou otn iad t.saaonnrilt A vrye rhsot npoe geiardn efarm ulodw tno meak a iaiinfgnsct rdefneiecf ni iblitay ot eb rntdstaeal hte( poen ngaerdi mfaer si het artp of hte mNRA aebl ot be asd.atn)etlr

get-ezeJrPush oreysdmn si an talmusooa noandtim resdonmy asaciosedt ihwt emgpeyperhidnt lcuasme on het mo,htu plsi, sadh,n adn gntlaaeei sa elwl sa seeadcrin kris of stbare dna GI rsnc.cea 20[AF20 7]83p

hisT iapettn npsteres ithw eth hsrccrtaieiatc dnmegheeyrppit luesacm sa elwl as otsvpiei olctcu olodb ttse hwhci doluc be ciativdien of na ynueingdrl GI ngcin.ayaml shrJtPugezee- is osal sidsacaoet whit ersomuun msaratmhoa rhogtuhuot hte IG rattc hwich codlu be soasdctiea thwi het pnasi'tte grealen GI smstyomp ude ot etirh yiitbla to ecaus bcoeglak.

etrhO a:rwesns

• ewonCd dsiaees - pmllieut aamhromat esoryndm htat ereicssna rksi fo taerbs, oryidh,t rinue,te and retoh secacr;n ti is tno tsacsdaeio hwit teh teppiynemgerhd scaeuml
• nearGrd synmrdoe - lifiamla oseanmudtoa pospilyso + usooses nda tfso eiutss msrtuo
• MrrToer-iu rnyeodsm - aerr eyrtheiadr malouatso ondniatm arcnce mrondyes hotthug ot eb a pybesut of CCPNH cLhn(y omnsr)dey
• osooasfurrmbetiNi - tno ssocaiatde iwth IG essuis dan liytpcayl ehav a yvre ridetnfef senntteioapr (002F2A 2p)55 - 1NF = cut-aalaeif- ss,opt lcihs nolde,su oce,ocmohmpohyart ueirs,zse coseanutu ,arfobrsemuion et;.c F2N = lraeitbla tuvabrseli mnw,hcaansos nlieeujvl eta,acsctr soegim,nmnai yosamdeempn

useDd nda tetesdu,d tle em tlle yuo ohw hihg iledy tmhaoPa h.C 3-1 ra.e Dr. Srtata si the grfnkaie na.m

wyy,Aan tshi is vsielerber lcle jyrnui eaescbu fo lnlgwsie. fI eht KNa/ AaePTs is ton ,rnkgowi aN is not ine.agvl aN oowllfs aetw,r so twera si ngtiteg custk in the elcl, nlgaide to .llnsgiew

osMt rottminap si izngrnecgoi htat s'ti eirlebsvre llec ijrnuy - gnyreihetv sele c(pteex KPF llo) is klngtai batou clle ahted

Thsi sinqtoeu cna eb ewrseadn yb a sresopc of oitinilaenm caprhopa ni ym :oonnipi 0220AF( p)863

• cseeBau eh hsa ssteet tath oem,rdf he ahs to aveh the YSR geen and usht eht Y roshcmmeoo cihhw emeaiinlst 64,XX dna 4X.,X7X
• ihsT is ton a nl-oormolkgina ipyobs nda eht ustqieno sska ouabt a rlcoaomshom bnytoiaralm so you acn eaniemtli 4Y6,.X
• Miosca aypetkyro 54X,6Y,X/4 is aedciatsso wthi eTu'rrsn nrodeys.m ehseT dldivainuis etpesnr wthi melafe alxenter naialgete nad teesst deeeudsncnd ro arlyer eseddndce tnoi eht labia maro.ja Teyh owlud otn veha rolctas s,sttee nda uhst thsi esiitmlnae thsi rsan.ew

Tish lvasee oynl ,X47YX which si Kefleisnre'tl nmyrsoed dna si datiseoasc twih eurttilsac ptayroh dan sxieevetn bfsoiirs nda yahnniizitloa iagdlne ot fli.itertniy

oFlw trae ( Q) = V * A
-V ocevytli A - srcso anctsoiel aare

uOr oclvtyie si ignev sa 0em2cc/s Cotnevr isth to cn/mmi ec2 /msc0 * oecs6d0ns = c102m/im0n

gulniPgg ni tsih lveua nito oru oiqtanue ofr wfol reat we tge 102i mc0n/m * 2 eurasq mc = 4200 ccbui mc /inm

otNe : 1000 cubci cm = 1 L d an tofereerh ew nac rovecnt uro enwsar ot Lim/n wchhi rea eth reeqidru usnti yb inidvidg by 0001

= 2.4 mLi/n