This boy has cystic fibrosis, which is caused by a defect in the CFTR gene which codes for an ATP gate chloride channel. The most common mutation leads to a misfolded protein (defect in protein structure) that results in the protein being retained in the RER and not transported to the cell membrane. (FA2020 p60)
tyrionwillCFTR is not a receptor which binds ligand to make a change of second messagers inside.
CFTR is a protein channel allowing ions in and/or out.
so choice B is wrong. +4
submitted by โcassdawg(1780)
This boy has cystic fibrosis, which is caused by a defect in the CFTR gene which codes for an ATP gate chloride channel. The most common mutation leads to a misfolded protein (defect in protein structure) that results in the protein being retained in the RER and not transported to the cell membrane. (FA2020 p60)