Praziquantel is one of the anthelminthic therapies used to treat cestodes and trematodes (FA2020 p200).
Specifically, this girl is presenting with Schistosoma mansoni, diagnosable by the appearance of the egg with a lateral spine in the stool (FA2020 p160). Schistosoma mansoni causes hepatosplenomegaly and ascites due to a propensity for infection of the liver leading to granulomatous reaction and fibrosis. Freshwater snails are the intermediate host with transmission occurring in freshwater, and specifically S. mansoni is found widely across Subsaharan Africa and parts of South America.
submitted by โcassdawg(1780)
Praziquantel is one of the anthelminthic therapies used to treat cestodes and trematodes (FA2020 p200).
Specifically, this girl is presenting with Schistosoma mansoni, diagnosable by the appearance of the egg with a lateral spine in the stool (FA2020 p160). Schistosoma mansoni causes hepatosplenomegaly and ascites due to a propensity for infection of the liver leading to granulomatous reaction and fibrosis. Freshwater snails are the intermediate host with transmission occurring in freshwater, and specifically S. mansoni is found widely across Subsaharan Africa and parts of South America.
Here is a good atricle for additional info on Schistosoma and its species.
The other important schistosoma to know is S. haematobium which infects the bladder and is associated with squamous cell carcinoma of the bladder.