NBME 21 Porphyria cutanea tarda (NBME Answers)

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NBME 21 Answers

nbme21/Block 4/Question#9 (reveal difficulty score)
A 60-year-old woman with psoriasis comes to ...
Porphyria cutanea tarda 🔍 / 📺 / 🌳 / 📖
tags: porphyria phototherapy

+10 upvote downvote
submitted by ∗imaginarybanana(30)

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with PCT you are supposed to avoid excessive sunlight and UV exposure. Methoxsalen makes your skin more susceptible to UV light.

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notadoctor Wouldn't UV light also be contraindicated in Vitiligo? +5

sweetmed Phototherapy with photochemotherapy (PUVA) is a well-known and well-studied modality for the treatment of psoriasis, which involves systemic or topical administration of chemicals known as psoralens and administration of ultraviolet light in increasing dosages after requisite time gap. PUVA is also used in the treatment of widespread vitiligo with moderately good results, though it is being surpassed by ultraviolet B (UVB), which is equally or slightly more efficacious with fewer side effects. +8

dashou19 Honestly, I didn't even know what Methoxsalen is, just chose the right answer because I know you can not give UV light to people with PCT... +14

sarahs what about tcell lymphoma which also has cutaneous lesions? +

shieldmaiden @notadoctor UVB from the sun is contraindicated. PUVA is actually used for vitiligo therapy +

+4 upvote downvote
submitted by ∗sweetmed(157)

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https://www.ncbi.nlm.nih.gov/pubmed/25382505

PUVA is used to treat Psoriasis and Vitiligo

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minion7 puva also used in GVHD +

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submitted by ∗castlblack(78)

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https://academic.oup.com/qjmed/article/107/11/945/2890493 PCT = vampires!

similar or same disease = Gunther's disease NSFL https://www.google.com/search?q=gunther+disease

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