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NBME 21 Answers

nbme21/Block 1/Question#2 (reveal difficulty score)
A 6-month-old girl is brought to the ...
GM2 πŸ” / πŸ“Ί / 🌳

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submitted by βˆ—imaginarybanana(30),
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'odnt eb a ick?d otn yalrle suer htaw mroe rethe is ot .ti heT ittapne 'etnods ahve nya rhteo yilmaf so shti waomn hudlos be eeidonscdr iymfla

submitted by βˆ—seagull(1746),
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! I heat ehtes hitw a igubrnn *Fi*g*n ispsano. bmshuT pu if ouy rgaee

mcl  Amen brother +2  
praderwilli  Every morning: "I think i'll go over glycogen storage diseases, lysosomal storage diseases, and dyslipidemias after questions this afternoon." Every afternoon: Nah +35  
mcl  oh my god are you me +2  
praderwilli  I recently found a program called Pixorize. It's pretty much Sketchy for biochem. Wish I discovered it sooner cuz it has helped for a lot of the painful things like this! +7  
burak  Cherry red spot basically means niemann-pick or tay sachs. Two differences between is: 1- No HSM in Tay Sachs, HSM in niemann-pick. 2- Both of them has muscle weakness but there is hyperreflexia in Tay Sachs, but areflexia in niemann pick disease. In stem cell HSM is not described and hyperreflexia noted. +5  
abhishek021196  What is HSM? +1  
mysticsoul  HSM - HepatoSplenoMegaly. Cherry red spots think of Tay Sachs, deficient enzyme - HeXosaminidase A, accumulated substrate GM2 ganglioside. Niemann-Pick - Spingomyelinase, Spingomyelin <- which is not even a choice. FA18 Pg 88 +1  
lakshmi  Dirty USMLE has an incredible video that makes these super easy to get. +3  
djeffs1  @lakshmi Link? +1  
drdoom  @djeffs1 +1  

submitted by βˆ—usmleuser007(435),
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1) eryV ormipttna ot neto thta yaa-TschS edissae ash remo nissvteei atelstr om()ro erlxef in soatnnee iwth naierscde adeh ecmrfenic.ceru

2) bFyar aedises = ndte to heav lsiva-udouia tefsced o/w lvier enlntiomevv

3) niNikn-emapc aidsees = emaina pm;a& iphaoytno wiht ailrexaef

submitted by βˆ—mcl(640),
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natePti mtos ellkyi sha aayc-TshS iasdese. iThs gfurie clieyn owssh eth hcomlciebia aa.phytw aelRcl thta hbot s-hyTcaSa dan aNnmine ciPk eesaisd pnretes ihwt a rercyh edr sotp on syucdnfoo,p tub ayT ahcSs lacks the algpolyemnpaeoesht nees ni NP.

hungrybox  Man this is such a nice figure except it doesn't have Krabbe disease :( +1  
mcl  Here's another one with Krabbe! :) +8  
hungrybox  thank u +3  

submitted by βˆ—isaacyo94(10),
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byoodN ash ieomdetnn eth eursp ihgh eilyd erdiytdm eeths ncminmeso have avdes em sosctulne i.mse.t. In this ec,as a" GNAG fo 6 lsmla "jesw elphs me emebermr ahtt sSxy)has(-iTac si a fccinedeiy ni the nmeezy sanXidsHomeiaE A si)(x, has an snieaecr ni MG2 lAeNG,idiGso nad 'etsodn reetnsp hiwt pmyllsehopteenoaga ml).a(ls


submitted by βˆ—basic_pathology(14),
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inceS yteh tbho eahv e-rcrhrdey p,tsos otw aesy ywsa ot ifdenerteftai eeentbw ThScyasa- S()T adn enniamN kPic )P(N:

)(1vpniser/eell: T:S lnamro ; P:N aelrg

(2) eag: ST: lt;6& to;mhsn NP: hhlldsdna/dooeceoicce

Bosnu: it kseta itme rl(doe aeg in NP) to odevpel mayoltsagnelphoepe H(MS in P)N

submitted by awabnaeim(0),
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I tkhni eht radxeteggea tatlesr ni yta ashcs si tylaclua edu to teh iyecshuapsr, hist si tenminedo ni isftr aid

submitted by swandy(3),
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eaGrt regiuf twhi lla eth omalslsyo tsroaeg ssae!dies

submitted by βˆ—burak(62),
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rhryCe der ostp cbsllyaai sneam incae-kpnnim ro aty shca.s oTw seernidfecf neeetwb si: 1- No SMH in yTa hcaSs, HSM ni mi-nkinn.cpea 2- tBho fo hmet hsa scemlu ekssneaw ubt etreh si xayirlrefpeeh in yTa scaSh, ubt elaefirxa ni inemnna pkci d.seseai In smet cell HMS si ton sdcbdieer adn rxeleyfpearhi .etond

burak  i mean, hyperacusis+hyperreflexia+sensitive startle +2  

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