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NBME 21 Answers

nbme21/Block 3/Question#1 (reveal difficulty score)
A 30-year-old woman develops dimness of vision
Ethambutol ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—hungrybox(1277)
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ethambutol = EYEthambutol

Great mnemonic for remembering that EYEthambutol is the component that causes visual problems in RIPE therapy for TB.

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hungrybox  RIPE = rifampin, isoniazid, pyrazinamide, ethambutol +2
l0ud_minority  Also sketchy remember the horse with Red-Green blinders +



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submitted by โˆ—mcl(670)
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Page 250 FA - Ethambutol is associated with visual disturbances (changes in color vision).

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dashou19  On FA page 250, it is said that Isoniazid can also cause optic neuritis and color vision change. Sometimes it hurts if you know too much lol +2



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submitted by โˆ—sd22(2)
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RIPE: Rifampin, Isoniazid (INH), Pyrazinamide, Ethanbutol.

RIPE treats TB.

Side Effects:

  • Rifampin: Red-orange metabolites. Skin/fluids can become red-orange. 'R'ifampin makes you 'R'ed
  • INH: Drug-induced lupus (DLE), iron accumulation in mitochondria (can lead to sideroblastic anemia), neuritis, and hepatitis. Give B6 for neuritis and SB anemia. INH has 3 letters like DLE
  • Pyrazinamide: Hyperuricemia (gout). pURICinamide
  • Ethanbutol: Effects eyes. Decreased visual acuity, red-green colorblindness. EYEthanbutol
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