NBME 22 Carboxylation of precursor proteins (NBME Answers)

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Retired NBME 22 Answers

nbme22/Block 3/Question#12 (reveal difficulty score)
An 82-year-old woman has been bedridden since ...
Carboxylation of precursor proteins 🔍 / 📺 / 🌳 / 📖
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submitted by ∗humble_station(85)

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frariaWn iibnhsit iVt K eetddnnpe snsysieht of csafort ;& oi.rnepst

iVt K is rayecness ofr eht tntiamroau of nitgoclt arocfst I,I II,V ,IX X nda penirto C m;ap& S

So a rdug ahtt can biitinh eht lniobxarctyao fo crrsepuro psiotrne ro in ertoh srowd ihtiibn the atanmuroit fo eht oitgtncl fcrtsao lwil seecadre the isrk fo tmrisboosh ni tihs eptia.tn

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Extra note: Thrombomodulin alpha (a recombinant drug) can increase thrombin degradation and Protein C activation, hence can also be used for anticoagulation. (But this question asked about decrease in which of the following)

+3/- apurva(101)

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+2 upvote downvote
submitted by ∗haliburton(224)

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rawrafni iniithsb teh sythesins of softacr ,II IVI, ,XI ,X C, dna S yb gobcknli otecrudin of xdieidoz atinmiv K. hTe enyzme pEdixoe Rseecudta is nibtideih yb fan.irraw heT eurcdde icat(v)e mrof of t.iv K si a atcfocor rof agamgmmt-ylalu aolsbcreyxa.

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link981 So otcfsar I,I IVI, XI, nda X are prosrucer npeoir?st OGTF +2

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submitted by ∗humble_station(85)

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inaafWrr ibniihst Vti K eendtenpd stiyenssh of tscfrao m&a;p netipos.r

tVi K si arsyensec rof teh iartotmanu of lticgtno rostafc II, VII, ,IX X and onpitre C p&ma; S

So a rgdu atth acn hbniiit eht alcnbxroytaoi fo rrsoueprc srpoinet ro in ehort rowds ibnihti eht itnuoaramt of teh cngttloi sortfac lwil sdeearce eht kris of oshomtsbri ni siht pettina.

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ajss ihts si why aiwnfrra is egivn as yirlsphpaox arfte shit teyp fo rrsiesgue +

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-2 upvote downvote
submitted by ∗sup(31)

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Why otn 2GIP by way of AS?A Ealeilpscy evgni troeh snrewa shoeicc fo sieropnt C + S: de'onst aawinrfr aols srussppe ese?ht

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imnotarobotbut Petroin C nda S are ,hotbT-irctIomAN so hhtogual nriarWaf seod eersaedc hemt, eyth towlnud' dseaerce teh estnapt'i kisr ofr oiotsbmrsh +1

epr94 hte qotuisen kas onpp"uiesr"ss fo hhiwc oen wlil sdraecee isrk of shrboomsti f i yuo psrusesp C and S hhwic adn mt-rtiaothconbi oyu teg ibtchmoort +3

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