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Retired NBME 22 Answers

nbme22/Block 1/Question#35 (reveal difficulty score)
A 35-year-old man is brought to the hospital ...
Alteration of the thermostatic set point ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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 +20  upvote downvote
submitted by โˆ—keycompany(351)
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tloAeairnt of eth ttsroacmhiet tse npoti is a hacitaplhmoy peoscrs deaitdem yb nisrndoaptgsal dan is eenpditennd fo the etipmchayst sevnour essymt.

,B ,C D, and E lla qireure pmecthitysa veesrn to ellicti a seesn.por

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pg32  naC anonye anxiepl eth mnihecsma bdneih ivhgensri dna eth csieympatht unesvor ?meytss +4
mdmikek89  hHmyapaotuls syeral rguhoht teh ctoanumio esourvn ys.tems You cut hte ryea,l you nca yonl canehg the imrsttcehaot est tionp, utb hte body nc'at recta. +1
umpalumpa  y,suG I hntik that rof hte nshreigiv rltetvnaeia the ptnoi si NTO ahtt hyipsttamce nesrev lotcnro nigehisrv cllat(yu,a I nhtvae' ofund csetiarl no epubmd atth assy that sgnevirhi is oorcltlend yb )h.ystatcimpe TeH stiaese way ot inkht is ahtt siht tp sah a cmtysies tcoeiinnf aak( SstRIe-mycSsi mlafyonaimtr rpoessne e.odysnmr) nI RS,IS tp cna evah ;tl35T& C ro g38&t; C, TUB ti is eomr nocmom ot ehva vfeer htan haemr.iohypt Crdnigisone t,sih uyo anc saleiy etuolu-r het vgnehirsi avnetaie.tlr +1

Even brown fat needs SNS == release of NE == binds to beta 3 receptor on fat == uncoupling of ox phos!

+6/- apurva(101)

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 +4  upvote downvote
submitted by โˆ—qfever(67)
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ytouaslmHpah otngrnlicol prtrmueteea tse itpon si lrbifey dnnetoiem ni taohamP 0182 nietdio epga ,31 atpherC 2 III alaniCrd gsisn of iofmnnlmatia .D Ferev

noePgyse tg-;& acmeaopghr eelrsea 1L-I nda FTN -gt&; dsecreani nyeaocsclegxoy tivaycit in slhhpytuoaam lavsiapurcre ellcs &-tg; aenisrdec halpoamhsuyt P2GE g&t;- deirsa rtmteerepua tse tpino

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 +0  upvote downvote
submitted by gribear(0)
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naC enomose nxaelip yhw hewn uyo scetratn eht apilsn odcr puersior ot het vlele fo tysceahtmpi lfouotw -- adn you get a emtcysis iofetcnni -- eth eenrpsos is nitelartoa of teh cittrehtsmao set pntoi?

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its_raining_jimbos  So I coshe ttha eon uecbaes est pinot is lrlootendc by hte supymhthaalo GE2P( nda -1IL deeatmi fveer ni eth hasmoultyap)h dan eht tsre of the reaswn cesciho dnvevloi hgtiesonm wbole eth vllee ahtt ahs eben ttcsand.ree tNo 1%00 ures if tโ€™atsh crteacua .uhohgt +5
noselex  dAeerg tiwh anj_tnsi_srgioi@imb -- erFev is ademtide yb gltaerni tes iotnp ni htomyuaas.hlp lAl het eroth hiceo,cs as arf as I can tel,l voenliv ahistmeptcy enresv nad rihet tsecfef at agttre sgan.ro +2

You might not be able to change the temperature because you have no sympathetic outflow, but the actual "resetting" of the thermostatic set point is mediated via the hypothalamus and prostaglandins

+2/- spow(50)

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 -1  upvote downvote
submitted by โˆ—j000(17)
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i tgo hsti ouisnqet nwog,r tbu i hktin ahtw shti uoneqsit si reayll ksgina is htwa npphsea in a smyctsie teofinn:ic hhicw si eferv

in mteiyscs eoi,ictfnn teh sotm sbuioov isgn to ookl fro is a everf, otn yscsinlerea vrgeih,isn ngwats,ie htea odirotpunc by bonrw taf, ec.t

dan who esdo veref ruocc? ekli ooesnme aayerld etioem:dnn pgenosey t-;-&g sagmoarehcp eealnsgri L1I adn FTN cihhw eisnresac OCX iyaitvct in yhsaohlmutap ucarsvearipl csel,l casenire urtpnodico of PGE2 ni lopyahmustah nad trees het pteurreeatm est in.otp

i khnit eth lehow ehpras pc"teemlo scniotntrea fo eth nliasp odrc prsiouer to hte leevl fo .pyaemtitch."s. is a .scrdiiatton it utsj lestl you tath eletedpomnv fo a vefre hsa ntgiohn ot od thwi ti

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j000  dpotmeeenvl of a vreef in smysiect encfntoii hsa gnhtnio ot od wthi aihpectymts uevorns ,lwof os vene st'i nd,eriuj frvee uodwl itlls ccou.r I ihntk tihs tsuoqeni is tjus aignsk ohw soed refev ocrcu ni imfo/tnitacinelamninof tnaiouis.t +1
b1ackcoffee  ,oS owh od oyu painexl teh acltua eefrv yb sjut aghnngci teh th??saetotrm rvFee 'tfecef' IS unerd ycthSimaept tnco,rlo jsut hte ahgnnigc the mrterepueta kile( e)thttarsmo si tdeidema by tncyioesk nad smt.auhaoplyh +2
j000  oh i ees tawh oyu nam,e ewll i in'tdd nowk that, os kstanh rfo giarciflyn a.tth owhv,ree based no rouy lo,paannteix it dowul itlsl teg su to hte hitgr rewsna wihch is rina"tltoae of ecsttohmirat set ,ipnt"o tno eth vefer ftefec t.slfei +1

So, how do you explain the actual fever by just changing the thermostat?? Fever 'effect' IS under Sympathetic control, just the changing the temperature (like thermostat) is mediated by cytokines and hypothalamus

+1/- b1ackcoffee(115)

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 -1  upvote downvote
submitted by โˆ—mdmikek89(6)
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Oyka osby dna igsrl hist qsnouite is sierea ahtn uoy h.nitk

pylaaoshmutH slreya aiv the peatctsyhim nursove sesmty to otclorn het doby wnhe a enw est ponti as nbee cdareeh ni lste u.f.rsac.ave.eyes.. .if.i.b.ne.cnyot

fI hte ceotinonnc ebtneew eth haualtmsyhop dna ipsnla rdco amn(ily teh mpitsceyaht ufool)wt si ut,c eth utlhsmaa oncatn yealr eth doyb aorcient of a vee,fr btu the spahltumahyo litfes can slilt ngeach eth est t.ipno

mBoo

Wintih hte ab,nir the uointmaoc ouvnesr etsmsy is gdtreeual by eht otayhmh.puals nAtimcoou nitnfoscu lndcuei ontoclr fo ,soitirnreap aairccd naleotrgui he(t criaadc ocrotln ,)ertenc soovmoatr vayttici teh( vmrosaoto ce)ten,r and irnteac lfrexe oisnatc hsuc sa uhn,ciogg sgneniz,e nwlwalsogi and gnvom.iti

E-B cuorc sa a rsuetl of a cehnag ni tse iopn.t

A psnphae to seauc the -EB wehn a new set pinot si aere.hcd

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 -1  upvote downvote
submitted by โˆ—isaacyo94(13)
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nI sycmsite niftnio,ec lodu'nwt yuo etg aeotucuns IsIaAODvTLNo .e(.i situbdirtevi ?okhs)c sTih wsa ym oisagennr rfo hgoocnis )B in shit cawky uqes.itno

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neilfespiritu  emSa +1


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 -3  upvote downvote
submitted by โˆ—gh889(154)
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mroF aokeooHdkenyrhunS on rdde:it

Wath het snoteuiq is tgtinge at si het yhmtaptiecs inahc aws p.rsdea tI saw a leretbri awy fo dirwong .ti

Yuor rnatorei lapmtauhohsy si snebeoirslp for iconolg uesratfe nad is dernu phacaypitmtarse ct.nrloo A elison uwldo saeuc rpmtyh.areehi

Yruo sertoopri ayotpslmuhah is esslenpobri rfo iehgnat hewn oeyru' oldc dan to egrtenea eth eFvre spoeerns and is reudn ahmysttpeci rc.tolno A niosle lwduo auecs iaemh.tyrpho

nI tihs unsotiqe it is lsmiyp skaing a rnpseo segt s,cik mthoaluahpsy saw ,pedras hwat eap.snhp

sn:eAwr pahltaousmhy wlil illst be bale to etleeva est dbyo ereatrupemt ot ltateb .ofennctii

nt:Hi IF eyth egiv a qtneiuos airlims ot hsit btu reewdord ot iendluc a isleon fo eht maceitptysh riebsf ro fo eth uhm,otpyhasal uyo oduwl ni utrn NTO be bael ot teergane a rvefe sproense to nofcetini. heT alhaypmshuot ouwld eb neyletir nuder cpheptariamtysa contlor

shiT sadd rome toentxc to the cfta het Q aetsts htat teh yistacemhpst wsa sadepr

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oslerweberrendu  S,o sith ysas ithemtyspca alos sderap nda phusoamahytl laos aedps.r nehT awht swa rgonw wthi sthi anliilcc esac?? +1
adong  i inthk het heyptatcmis tsyems is actaulyl mpidaier b/c 'sit ctu efroeb ti can .ot"l"fw.o.aut satel 'tsi eht nylo yaw tshi ekmsa ensse +4
suckitnbme  I aege.r I kniht eht toseqnui emst si aiyngs teh yepissmthcat ewre ielsed.on Not hatt eyht weer seard.p +4


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