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NBME 15 Answers

nbme15/Block 3/Question#18 (reveal difficulty score)
A 27-year-old man comes to the physician ...
Prolonged fecal excretion of the organism ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: pharm

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 +12  upvote downvote
submitted by โˆ—cassdawg(1780)
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FA2020 p144

An USMLE testable fact about salmonella species is that antibiotic use actually prolongs the excretion of the organism. Fun fact(?) for memorization as there is no clear answer as to why that I could find.

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hiroshimi  Have a card in Zanki saying this using abx with salmonella can cause HUS so may be it's linked? +



 +1  upvote downvote
submitted by โˆ—whk123(23)
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-Few data shows that antibiotics (ABs) are helpful in treating Salmonella gastroenteritis (as it may prolong the illness). It is difficult to treat because of lots of antibiotic resistance. ABs are used in severely ill patients only. ABs are not of benefit in uncomplicated cases. In fact, ABs may prolong the period in which you carry the bacteria and can infect others, and they can increase your risk of relapse. Side note: Anti peristalsis med like loperamide are contraindicated.

-For typhoid fever, some people take ceftriaxone, fluoroquinolones.

-In comparison, Shigella is kinda sweet in this matter that ABs ingestion improves symptoms, reduces shedding in the stool so others won't get sick and hence can limit spread.

[Salmonella and ABs treatment outcome] (https://www.mayoclinic.org/diseases-conditions/salmonella/diagnosis-treatment/drc-20355335)

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