Our patient in DKA has high glucose outside her cells that will be taken up when insulin is administered. Glucokinase is the first step in glycolysis and will increase as the glucose is used. The other enzymes represent pathways that will be inactivated when insulin is given/in high glucose state (gluconeogenesis etc.) Insulin fa2018 p322
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Glucokinase expression is induced by insulin and helps to store glucose in the liver. FA 2019 p. 75