He has alpha-1 antitrypsin deficiency which is causing panacinar emphysema and liver damage. This is the major disease to think of when you have a young-ish patient who presents with liver and lung issues. (FA2020 p392)
From the stem: hyperinflation combined with decreased diffusion capacity and decreased FEV1 points toward emphysematous change; lower lobe predominance is seen in panacinar emphysema; hepatomegaly pointing to liver involvement
NOTE: diffuse idiopathic interstitial fibrosis would cause a decreased diffusion capacity, but this is a restrictive lung disease which would not have hyperinflation but instead decreased lung volume
lucifer546hyperinflation rules out IPF
decrease diff capacity rules out asthma (it is actually increased in asthma)
marijuana is not associated with pulmonary disorders as such+1
submitted by โcassdawg(1780)
He has alpha-1 antitrypsin deficiency which is causing panacinar emphysema and liver damage. This is the major disease to think of when you have a young-ish patient who presents with liver and lung issues. (FA2020 p392)
From the stem: hyperinflation combined with decreased diffusion capacity and decreased FEV1 points toward emphysematous change; lower lobe predominance is seen in panacinar emphysema; hepatomegaly pointing to liver involvement
NOTE: diffuse idiopathic interstitial fibrosis would cause a decreased diffusion capacity, but this is a restrictive lung disease which would not have hyperinflation but instead decreased lung volume