NBME 15 Inadequate hydroxylation of collagen polypeptides (NBME Answers)

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NBME 15 Answers

nbme15/Block 2/Question#24 (reveal difficulty score)
An 82-year-old woman with alcohol dependence ...
Inadequate hydroxylation of collagen polypeptides 🔍 / 📺 / 🌳 / 📖
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submitted by ∗cassdawg(1780)

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This woman has the classic signs of vitamin C deficiency, or scurvy: easy bruising, petichiae, perifollicular hemorrhages, gum disease, and slow wound healing. Vitamin C is necessary for proper hydroxylation of proline and lysine in collagen. (FA2020 p69 [nice])

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submitted by ∗mannan(18)

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Defective cross linking of elastic fibers is Ehlers Danlos syndrome

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