NBME p2ck_form8 Toxin-induced inflammation of the colonic mucosa (NBME Answers)

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A 57-year-old woman comes to the physician ...
Toxin-induced inflammation of the colonic mucosa 🔍 / 📺 / 🌳
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+2
submitted by ∗step_prep(115),

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entaPit ihtw ncrtee oiciitabnt ugaes dvelseop eserev raiaehdr dna naamobdli a,ipn hihwc is tmos inotentssc whit .C lfidefiic oinifcetn
Kye dia:e C. fildfiiec ldsea to aaheidrr by donriucpg two ainm xtnsoi thta aeld to ytrnoceete agmdea
yKe :diea oixTc elomaocgn nac eb enes ernsyacdo ot C. fdliiefic otfeniicn adn iucrtvalee iicsotl (at telsa fro EMBN osspr)eup

s-e./hs/p:pttrptoerpg/

seagull I choose sterilization because C-diff is essentially an imbalance of colonic flora due to antibiotic "sterilization" leading to expansion of C. Diff. However, I ca see how toxin- mediated is the true mechanism but the question seems dirty to me. +7

jd1 I think also technically sterilization refers to inactivating spores (as opposed to disinfection which would not), so would imply Cdiff would be killed off too +6

+1
submitted by ∗jlbae(105),

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OMI, tshi wsa a iytths utqnsioe. nuP eyrv cmhu ine.tndde

+0
submitted by ∗charcot_bouchard(519),

I also first chose sterilization but later move it to toxin. Its very straight if u look at it that toxin is the one causing diarrhea. Sterilizing gut flora occrs everytime u take antibiotics, its predisposing to C. DIff but not actually causing diarrhea otherwise everyone would get it.

+0
submitted by ∗kstudy(3),

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htis si a treag pealexm of hyw I gusrgetl iwht ihst ilyls mnbe dna petss. erA ew nitgest nekgleowd heer or ienasmst?c