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NBME Step 2 CK Form 7 Answers

step2ck_form7/Block 1/Question#34 (reveal difficulty score)
A previously healthy 24-year-old woman comes ...
Decreased acetylcholine receptors ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
tags: msk repeat

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submitted by โˆ—step_prep5(246)
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  • Presentation is most consistent with myasthenia gravis (young woman or older man presenting with dysphagia, dysarthria and eye weakness that is worse at the end of the day), which is caused by antibodies attacking acetylcholine receptors and leading to reduced acetylcholine receptors
  • Decreased release of Ach from motor nerve terminals = Lambert-Eaton syndrome
  • Degeneration of muscle fibers = Muscular dystrophy

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cbreland  I thought the binding of the antibodies causes an increase in receptors.... Idk got the question right, but just because none of the other answers made sense to me +1
link981  To further differentiate Myasthenia Gravis from Lamber Eaton: Deep tendon reflexes are normal in Myasthenia Gravis, not so in Lambert Eaton +



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