This patient has gestational trophoblastic disease as evidenced by the extreme B-hCG concentration below 20 weeks gestation, no fetal heart sounds, large uterus, and the round densities in lung + shortness of breath
Young pregnant woman who presents with enlarged uterus (uterus to umbilicus consistent with gestational age of 20+ weeks), absent fetal heart tones, severely elevated beta0hCG and chest x-ray showing multiple densities (โcannonball metastasesโ) most consistent with choriocarcinoma
Key idea: Rare diagnosis that can develop during pregnancy, after delivery or after abortion
Key idea: Can be associated with symptoms related to increased hCG due to alpha subunit of hCG being the same as the alpha subunit of LH, FSH and TSH, including early pre-eclampsia, hyperemesis gravidarum, hyperthyroidism and theca-lutein cysts
submitted by โmedgirl11(20)
This patient has gestational trophoblastic disease as evidenced by the extreme B-hCG concentration below 20 weeks gestation, no fetal heart sounds, large uterus, and the round densities in lung + shortness of breath