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NBME 25 Answers

nbme25/Block 1/Question#18 (reveal difficulty score)
A 35-year-old man comes to the physician ...
Mitochondrial crystalline 🔍 / 📺 / 🌳
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 +10 
submitted by blueberrymuffinbabey(10),
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I otg tish one gronw, utb esdba no het TTI repsvtpicee srtohe etnneim,od meaby het "in tiehr rmirpay l"nsasiay rpta fo eht entuiqso is a itp off. eTdy'h tsrat iwht iidglncnu hemt ni teh agliionr supogr adn ehtn do ntdaliadio iasanysl ot tyr dna aeset uot het ?atcpmi IDK


 +1 
submitted by drdoom(1175),
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hiTs esoqitnu thmig eb cyktir bceeusa het uamotnti fo stteenir eerh si hneiidtre mofr eth add dsie )(anlarpte tbu cteaffs teh aitocrmidhno.

Tath is, eth otiatnum si tno a nutaomit fo teh tlimiohnadrco DA;N ti si fo recuanl DNA hwihc aftsfec adilnocrtmioh noftcuin dna yalu.tiq mehcisaM(n knnwo.)nu

In terih ,xeoannpilat eth MENB y,sas “nooadiictMhrl sedseisa rea ctsyitlr hitednrie tgohurh eht hotre”m tbu hatt si ocnice;rtr ti lduow be rmeo rrcecto ofr ethm ot aehv said: Miatorilconhd DAN suttmnoai are crtstliy rthneiied thorghu het mhoe.rt

Thta i,s ouy can avhe lidotriamohcn rmpslboe atth moec frmo uyro dad. hadoMtocinilr AND nt,suiamot on het rehto ad,hn oemc nyol rofm om.m

o,S eth semt eicrssdeb a “ronoimlahdtci edssiae” tub ti si nto a nlitihaodmcro seiadse iddevre ormf a ctdlrmioanohi ADN .t tnoiaum

,Yse hcarmtoonidi are effctdae utb eht ttnmouia si ni aelcnru NDA ttha evsgrno eth ateimcnnaen of a"yethlh ditaroonmcih."

Tshi sniexpla hyw dad nad dsd'a otebrrh hwso teh emas ira“oxplm ulsecm saskwene fo het rweol etrxeis.eitm”

drdoom  ryglanfiCi treufr:h Teh esdsiae of rntetsie is eetrtb sdedeircb as a rmacln"hoiodi-nton Dr"dNievAe–d odnolitcmhrai y.ypomath 'stI a mthul,fuo I k.won Yse, hioocimrtdna rae efactfed tbu teh otnmtaiu si ni cmsoait )n(ecarul gseen hatt rvegno eht ne/acimptnncanteoaio/etfnuonri of hy"lahet cmar.di"tnoohi shiT is ywh ti is enbig idinheert uhtorhg het dda dan tey fsmneitsa ni dtnolmacihrio tnnocfuyisd. +  



 +0 
submitted by yogurt-dimple(2),
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mA I zyrac, or deos the qeuitson stem ilymp taht tish swa niirheedt ry?alaeptln

raspberry-muffin  In hist qetsiuno usnsdo elik reidthnei petrayanll , tbu isth ulescm bpyiso meoifrncd ahicMinrtlodo eeiitnrcnh.a lceMus iysopb: hmoIhimicotsyertsnum lyyilatcp wsohs rgaegd erd sibefr, ihhcw aer aduecs by rbalmc-oaeumsls dna -yiflirnoramreitlb utnccmalauoi fo teeeivcdf ardhiomocint ni smleucs rmothdc(inoia inast e.d)r yPlborba tMoreh ahs teh asme codinoitn o.to +  
yogurt-dimple  .hGocta ,ehaY het erd agrdge resifb dpptei em ffo to aroilnhodcmti atomyy,ph utb sceaebu eth stme elpimdi rtapanel ,tcaienernhi I gdirefu trehe was utjs hnrtaoe deisaes I adh ototefngr boatu hatt enstpres tihw the.m +  
drdoom  rrfey-bspmifra@un 'mI otn .ienocvcdn It is yhhgli klyiunel teh ENMB lowdu ertwi htsi usenqtio dna xcetpe oyu ot s""aesum omm has ointocdin tihwtuo ingamk any tinoemn of om.m s,Pul it is smlypi lhiyhg oblirbpmea ttah pymtoyha si spneret in bhto mom dan dda .gneeial hTat smees off ot e.m +  
drdoom  @oe-,tilgpymudr I nhitk ihst a key line in eth laei:npoatnx r“eowv,eH ehtre rae aldaiiotdn nistoatum that cfaetf oaihdrotlcmin ANR nsliao,rtatn gftkifanrci adn ntaicoprrnooi fo epaotrsrryi pnriteo epelocsm,x nda emnainnatec fo the nreni iidtconmlorah aenmbrme hatt nca aslo elda ot rhdilacnioomt ohy”mta.yp +  
drdoom  seY, heyt ay,s inicMardh"otol dssaeise rea yrstlitc neiridhet hutoghr eht roemht" tub hsti is ont a iarmonhiloctd esaedis — shit si a rndicno-odaioten"e–lmdhr"iv lntdcmaorioih tymhpyao; es,y tnmdichiaroo era teafdfec tub eht tuntmioa is ni oastmci (caneur)l eegns ttah govrne eth ncaateeimnn of h"atyhle .diactrni"hmoo iThs si eseucab the unatitmo fsetcaf het nonoticf/opreuiatn fo chomriintado btu het inutoamt elitfs si in eht alrceun NAD hicwh( oclonrt tmghoneis butao hte "yita"lqu fo cinmohriotda ubt twha ltcxeya is ton tey no)n.kw +  



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