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NBME 23 Answers

nbme23/Block 4/Question#18 (54.8 difficulty score)
An investigator is conducting a study to ...

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submitted by drsquarepants(19),
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I ufodn iths ,uepflhl vneoledep sv. lveneodnnope

drsquarepants  Chart on slide 22 +6  
megaera13  Thank you. Definitely need to note this down somewhere. +2  

submitted by thomasalterman(161),
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Evosneelp itfeenb the iuvrs in that the virus lwil oklo liek hte sth,o iifcttaiangl oisfun. o,eevwrH an dlpeenove rusiv si aerelngly less aelstb anht a nedak ldisoheacra iuvsr nkaed( siseuvr are rlngealye lhr)i.adasoce

docred123  So do these patients have h.Flu? What was the giveaway? Thanks +2  
mousie  I chose Enveloped simply bc it said dies when heated, not sure if there where any other clues to narrow this down or make me feel more confident in my choice but I went with it anyway +16  
eclipse  I don't think they expected us to narrow down the answer to a specific virus. Enveloped viruses tend to be less stable (?) than the non-enveloped ones and don't survive as well under harsher environments (outside human's body, heat, etc.) +2  
peridot  To add on, I also have no idea what virus this could be but the question stem does say "A previously unidentified virus is recovered from urine specimens" making me think that it's not something we're supposed to have know about, unless I'm totally understanding it wrong. +1  

submitted by lamhtu(124),
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A oeiplssb oenatntrigi to eplh tiwh giwernnas shti i:tseuqon rcotcSmhkeyi tsetas oen bossiepl wya to eiitacvnat eirnvseausar si .teha israAsvnereu rea od.eepnvel fI uoy cna eeemrrbm s,thi uyo nca keep tihgrsta htta vpdeneole sveiurs era -hilatlaeeb nie(vse)tsi

submitted by underd0g(11),

My last-ditch reasoning was that SPORES are heat-resistant; therefore enveloped viruses must not be.

submitted by brise(65),

AKA the reason why covid can be killed with heat! B/c it is enveloped!

submitted by amy(1),
  1. The non-enveloped virus are tougher than enveloped virus (think HAV and HEV vs HBV)
  2. Heat labile: Microorganism destroyed at 60C Heat stable: Microorganism survive 100C for 1h

In this question, viral infectivity is destroyed at 60C, which mean it is not as tough, so envoloped.