This is Dissiminated Intravascular Coagulation (FA2020 p428)
DIC is a consumption coagulopathy (clotting factors are activated EVERYWHERE so they quickly produce microthombi and are consumed, allowing for bleeding). Thus, the individuals present with a consumption of coagulation factors leading to increased bleeding time, increased PT/INR, increased PTT, low fibrinogen and other clotting factors as well as a consumption of platelets leading to thrombocytopenia. Because there is widespread clotting factor activation, they also have signs of widespread microthombi sich as schistocytes and increased fibrin degradation products.
submitted by โcassdawg(1780)
This is Dissiminated Intravascular Coagulation (FA2020 p428)
DIC is a consumption coagulopathy (clotting factors are activated EVERYWHERE so they quickly produce microthombi and are consumed, allowing for bleeding). Thus, the individuals present with a consumption of coagulation factors leading to increased bleeding time, increased PT/INR, increased PTT, low fibrinogen and other clotting factors as well as a consumption of platelets leading to thrombocytopenia. Because there is widespread clotting factor activation, they also have signs of widespread microthombi sich as schistocytes and increased fibrin degradation products.