Patient with Primary Hypothyroidism (problem with the gland itself ) treated with T3
In normal physiology T4 is converted to T3 and less commonly ( rT3) . As such most of the T3 in the body is derived from the peripheral deiodination of T4 to T3
Also note that TSH secretion by anterior pituitary is under negative feedback control by both Free T3 and T4
So what happens when we give our Patient T3.
- firstly , we inhibit secretion of TSH from the pituitary gland . ( TSH decreases ).
This means less stimulation of the Thyroid and less hormone production . The Throid hormone it primarily makes and releases is T4 , ( and so T4 decreases ) . Naturally you would also expect a decrease in T3 but patient is taking exogenous T3( and so T3 increases )
schepI messed this up because I know treatment of primary hypothyroidism is usually with levothyroxine (T4). I totally skimmed the part where we are told she is being treated with T3+3
submitted by โandro(269)
Patient with Primary Hypothyroidism (problem with the gland itself ) treated with T3
So what happens when we give our Patient T3.
- firstly , we inhibit secretion of TSH from the pituitary gland . ( TSH decreases ).
This means less stimulation of the Thyroid and less hormone production . The Throid hormone it primarily makes and releases is T4 , ( and so T4 decreases ) . Naturally you would also expect a decrease in T3 but patient is taking exogenous T3( and so T3 increases )