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NBME 17 Answers

nbme17/Block 0/Question#0 (reveal difficulty score)
18-month-old girl is brought, separation of ...
Leukocyte adhesion and transmigration ๐Ÿ” / ๐Ÿ“บ / ๐ŸŒณ / ๐Ÿ“–
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submitted by โˆ—cassdawg(1780)
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FA2020 p116

Leukocyte adhesion deficiency presents with late separation of the umbilical cord, absence of pus (since pus is made of neutrophils), and dysfunctional neutrophils leading to recurrent skin and mucosal infection

LAD is due to a defect in LFA-1 integrin on phagocytes causing deficiency in adhesion and transmigration.

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andro  LFA-1 also known as beta 2 Integrin ( CD 18) +2



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