Hep C - RNA virus (not enveloped) (picorna family + ssRNA).
Viruses are intracellular- so their products are displayed on MHCI molecules (using tap1/tap2 to shuttle the viral proteins broken down by proteosome) and are shipped to the cell surface of infected cells. Since this is MHC I we know CD8+ t cells (cytotoxic T lymphocytes) are responsible for attacking the infected cells.
submitted by โtopgunber(67)
Hep C - RNA virus (not enveloped) (picorna family + ssRNA).
Viruses are intracellular- so their products are displayed on MHCI molecules (using tap1/tap2 to shuttle the viral proteins broken down by proteosome) and are shipped to the cell surface of infected cells. Since this is MHC I we know CD8+ t cells (cytotoxic T lymphocytes) are responsible for attacking the infected cells.